EP-1352: Early clinical experience from MRI-only based radiotherapy of localised prostate cancer

Surgery versus radiotherapy for localised prostate cancer

TRIAL EVIDENCE LACKING Despite millions of men having undergone these prostate cancer treatments, no randomised controlled trial evidence currently exists to compare their effectiveness. The only such trial underway, the ProtecT study, will not report until 2016 and may have limited generalisability due to differences in the randomised population and the prostate cancer population at large.3 Al...

Technologies for early localised prostate cancer

Dosimetric and Radiobiological Evaluation of Multiparametric MRI-guided Dose Painting in radiotherapy of Prostate Cancer

Introduction: Radiotherapy is one of the treatment options for locally advanced prostate cancer, however with standard radiation doses it is not always very effective. One of the strategies to improve the efficiency of radiotherapy is increasing the dose. In this study to increase tumor local control rates a new radiotherapy method, known as dose painting (DP) was investigated....

Early clinical experience of radiotherapy of prostate cancer with volumetric modulated arc therapy

BACKGROUND To report about initial clinical experience in radiation treatment of carcinoma of prostate with volumetric modulated arcs with the RapidArc (RA) technology. METHODS Forty-five patients with a median age of 72 +/- 3, affected by prostate carcinoma (T1c: 22 patients, T2a-b: 17 patients, T3a-b: 6 patients. N0: 43 patients, N1-Nx: 2 patients, all M0), with initial PSA of 10.0 +/- 3.0 ...

Early toxicity of moderate hypofractionated volumetric modulated Arc radiotherapy for localized prostate cancer

Background: Based on the radiation biology model of prostate cancer, hypofractionated radiotherapy can improve the treatment outcomes without increasing toxicity. Although hypofractionated radiotherapy is implemented over a short period of time, it is more convenient and cheaper compared with conventional fractionated treatment. The aim of this study was to investigate the early toxicity of mod...